CARMAT : Indicators a Partnership Settlement with AddUp, the Michelin and Fives Joint Enterprise Specialised in 3D Printing | Four-Merchants

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This distinctive collaboration within the medical sector will speed up the
industrial section of the CARMAT challenge

Regulatory Information:

CARMAT (Paris:ALCAR) (FR0010907956, ALCAR), the designer and developer
of the world’s most superior synthetic coronary heart challenge, aiming to supply
a therapeutic different for individuals affected by end-stage
biventricular coronary heart failure, in the present day pronounces that it has signed a
partnership settlement with AddUp, the Joint Enterprise specialised in 3D
printing arrange by the Michelin and Fives teams.

The goal of this collaboration is to strengthen the commercial
growth of the CARMAT coronary heart and contribute to extend the Firm’s
manufacturing capability in preparation for the big scale manufacturing section.

Because of AddUp’s experience, CARMAT will in the end be capable to present
surgeons and sufferers with a model of its synthetic coronary heart that
incorporates all of the technological advantages of 3D printing, and in
explicit:

  • optimized anatomical interfaces resulting in enhanced anatomical
    compatibility and surgical consolation;
  • discount within the variety of elements, thus higher securing the
    system’s meeting.

Vincent Ferreiro, CEO and Chairman of AddUp, feedback: “As
pioneers within the growth of commercial 3D printing options, we’re
delighted to have the chance to affiliate our distinctive additive
manufacturing know-how with a medical challenge as revolutionary because the
CARMAT one. We possess a know-how in offering assist to our companions
from the feasibility stage to the industrialization of idea concepts. We
are very enthusiastic concerning the skill to use it to the medical area
for the primary time.”

Stéphane Piat, CEO of CARMAT, provides: “The CARMAT challenge has
been, for the reason that starting, an ideal instance of cooperation between the
industrial and medical fields. The partnership settlement signed in the present day
with AddUp is a further proof and can allow us – alongside our
ongoing scientific growth – to
anticipate longer-term
evolutions in our industrial and technical wants. With a accomplice as
prestigious as AddUp, I’m satisfied in our skill to speed up our
industrialization and safe our challenge.”

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About AddUp

AddUp was created on April 1, 2016 following the choice adopted by the
two main industrial teams Fives and Michelin to create, on September
Four, 2015, Fives Michelin Additive Options. This three way partnership goals to
convey prospects its distinctive expertise and experience in growing and
advertising and marketing machines and industrial manufacturing strains utilizing steel additive
manufacturing know-how, commonly known as steel 3D printing,
worldwide.

About CARMAT: the world’s most superior whole synthetic coronary heart challenge

A reputable response to end-stage coronary heart failure: CARMAT goals to
finally present a response to a serious public well being concern related
with coronary heart illness, the world’s main reason for loss of life: power and
acute coronary heart failure. By pursuing the event of its whole synthetic
coronary heart, CARMAT intends to beat the well-known shortfall in coronary heart
transplants for the tens of 1000’s of individuals affected by
irreversible end-stage coronary heart failure, probably the most critically affected of the
20 million sufferers with this progressive illness in Europe and the
United States.

The results of combining two kinds of distinctive experience: the
medical experience of Professor Carpentier, identified all through the world
for inventing Carpentier-Edwards® coronary heart valves, that are the
most used on this planet, and the technological experience of Airbus Group,
world aerospace chief.

Imitating the pure coronary heart: given its measurement, the selection of
structural supplies and its revolutionary physiological features,
CARMAT’s whole synthetic coronary heart may, assuming the mandatory scientific
trials are profitable, doubtlessly profit the lives of 1000’s of
sufferers a yr with no danger of rejection and with a very good high quality of
life.

A challenge chief acknowledged at a European stage: with the
backing of the European Fee, CARMAT has been granted the biggest
subsidy ever given to an SME by Bpifrance; a complete of €33 million.

Strongly dedicated, prestigious founders and shareholders: Airbus
Group
(Matra Défense), Professor Alain
Carpentier
, the Centre
Chirurgical Marie Lannelongue
,Truffle
Capital
, a number one European enterprise capital agency, ALIAD, Air
Liquide’s enterprise capital investor, CorNovum, an funding holding
firm held 50-50 by Bpifrance and the French State, the household places of work
of Pierre Bastid (ZAKA) and of Dr. Antonino Ligresti (Santé Holdings
S.R.L.) in addition to the 1000’s of institutional and particular person
shareholders who’ve positioned their belief in CARMAT.

For extra info: www.carmatsa.com

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Disclaimer

This press launch and the knowledge contained herein don’t
represent a suggestion to promote or subscribe to, or a solicitation of an
supply to purchase or subscribe to, shares in CARMAT (“the Firm”) in any
nation. This press launch accommodates ahead‐wanting statements that
relate to the Firm’s aims. Such ahead‐wanting statements are
based mostly solely on the present expectations and assumptions of the
Firm’s administration and contain danger and uncertainties. Potential dangers
and uncertainties embody, with out limitation, whether or not the Firm will
achieve success in implementing its methods, whether or not there shall be
continued development within the related market and demand for the Firm’s
merchandise, new merchandise or technological developments launched by
opponents, and dangers related to managing development. The Firm’s
aims as talked about on this press launch is probably not achieved for
any of those causes or resulting from different dangers and uncertainties.

No assure might be given as to any of the occasions anticipated by the
forward-looking statements, that are topic to inherent dangers,
together with these described within the Doc de Référence filed with the
Autorité des Marchés Financiers
underneath quantity D.16-0200 on March 22,
2017 and adjustments in financial circumstances, the monetary markets or the
markets wherein CARMAT operates. Specifically, no assure might be
given in regards to the Firm’s skill to finalize the event,
validation and industrialization of the prosthesis and the tools
required for its use, to fabricate the prostheses, fulfill the
necessities of the ANSM, enroll sufferers, acquire passable scientific
outcomes, carry out the scientific trials and checks required for CE marking
and to acquire the CE mark. CARMAT merchandise are presently solely
used inside the framework of scientific trials.

●●●

Title: CARMAT
ISIN code: FR0010907956
Ticker: ALCAR

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